Detalhe da pesquisa
1.
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Cell
; 184(12): 3143-3162.e32, 2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34004147
2.
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.
Mol Cell
; 81(10): 2183-2200.e13, 2021 05 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34019788
3.
Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma.
Proc Natl Acad Sci U S A
; 120(36): e2306414120, 2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37643213
4.
JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias.
Genes Dev
; 32(11-12): 849-864, 2018 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29907650
5.
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Nature
; 560(7717): 253-257, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30069049
6.
Targeting Bfl-1 via acute CDK9 inhibition overcomes intrinsic BH3-mimetic resistance in lymphomas.
Blood
; 137(21): 2947-2957, 2021 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33259592
7.
Efficient CRISPR/Cas9 Gene Editing in Uncultured Naive Mouse T Cells for In Vivo Studies.
J Immunol
; 204(8): 2308-2315, 2020 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152070
8.
T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.
Nature
; 538(7626): 518-522, 2016 10 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-27750279
9.
Whole genome CRISPR screening identifies TOP2B as a potential target for IMiD sensitization in multiple myeloma.
Haematologica
; 106(7): 2013-2017, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33375771
10.
Constitutive type I interferon modulates homeostatic balance through tonic signaling.
Immunity
; 36(2): 166-74, 2012 Feb 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-22365663
11.
Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Immunity
; 36(4): 561-71, 2012 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22483801
12.
BET inhibitor resistance emerges from leukaemia stem cells.
Nature
; 525(7570): 538-42, 2015 Sep 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26367796
13.
IL-15 Preconditioning Augments CAR T Cell Responses to Checkpoint Blockade for Improved Treatment of Solid Tumors.
Mol Ther
; 28(11): 2379-2393, 2020 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32735774
14.
SnapShot: Extrinsic apoptosis pathways.
Cell
; 143(7): 1192, 1192.e1-2, 2010 Dec 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21183080
15.
Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population.
Blood
; 129(21): 2882-2895, 2017 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28283481
16.
DOCK8 Drives Src-Dependent NK Cell Effector Function.
J Immunol
; 2017 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28794229
17.
Functional-genetic dissection of HDAC dependencies in mouse lymphoid and myeloid malignancies.
Blood
; 126(21): 2392-403, 2015 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-26447190
18.
Long term, continuous exposure to panobinostat induces terminal differentiation and long term survival in the TH-MYCN neuroblastoma mouse model.
Int J Cancer
; 139(1): 194-204, 2016 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26914605
19.
Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.
PLoS Pathog
; 10(10): e1004473, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25393648
20.
Id2 represses E2A-mediated activation of IL-10 expression in T cells.
Blood
; 123(22): 3420-8, 2014 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24723679